During cell division in a mother cell, the 23 chromosomes that carry the human genome must be first copied and later delivered to two newly forming daughter cells. At least in healthy cells, the result is astonishingly flawless, ...
Molecular & Computational biology
Apr 8, 2022
0
72
For reproduction to be successful, an egg cell must divide perfectly. Egg cell divisions are so error-prone, however, that they are the leading cause of miscarriages and birth defects in humans.
Cell & Microbiology
Mar 29, 2022
0
132
Human eggs often contain the wrong number of chromosomes, leading to miscarriages and infertility. A research team led by Melina Schuh at the Max Planck Institute (MPI) for Multidisciplinary Sciences has discovered that human ...
Cell & Microbiology
Feb 11, 2022
0
66
The error-free division of mouse oocytes—the precursors of eggs—needs kinetochores that are rich in a specific microtubule crosslinker, RIKEN researchers have discovered. This finding could explain why the division of ...
Plants & Animals
Jul 31, 2020
0
19
An over-abundance of the protein PRC1, which is essential to cell division, is a telltale sign in many cancer types, including prostate, ovarian, and breast cancer. New research, published online today in Developmental Cell, ...
Cell & Microbiology
Jul 7, 2020
0
84
Fleets of microscopic machines toil away in your cells, carrying out critical biological tasks and keeping you alive. By combining theory and experiment, researchers have discovered the surprising way one of these machines, ...
General Physics
Sep 2, 2019
1
477
Researchers at the University of Dundee have solved one of the mysteries of cell division, a discovery which may shed light on cancer development and one day help develop new drugs to treat the disease.
Cell & Microbiology
Jul 31, 2019
0
170
Researchers at Dartmouth College have revealed how a key protein functions during the millions of cell divisions that occur in the human body each minute. The research describes two separate but coordinated pulling actions ...
Cell & Microbiology
Aug 7, 2018
0
60
It was long thought that during an embryo's first cell division, one spindle is responsible for segregating the embryo's chromosomes into two cells. EMBL scientists now show that there are actually two spindles, one for each ...
Cell & Microbiology
Jul 12, 2018
0
165
An important complex forming the core of the cell division apparatus in stem cells has been imaged using the Macromolecular Crystallography beamlines, I04 and I04-1 at Diamond Light Source. As recently reported in Nature ...
Cell & Microbiology
Apr 9, 2018
0
29
