Aldehydes are toxic compounds that are produced in the body by metabolic processes, especially upon alcohol consumption. They are dangerous because they bind to cellular macromolecules, such as DNA, RNA, and proteins, and ...
Cell & Microbiology
Nov 15, 2023
0
9
A research team led by University of California, Irvine scientists has developed an innovative method for quickly and efficiently creating vast collections of chemical compounds used in drug discovery by harnessing the power ...
Biochemistry
Aug 23, 2023
0
78
Two proteins come together to protect and stabilize RNA as it carries muscle-forming code through the cell. Further understanding this RNA-stabilizing complex may have implications for influencing muscle recovery and disease ...
Cell & Microbiology
Mar 8, 2023
0
44
Messenger RNA (mRNA) are biological molecules that transfer the information coded by genes in the nucleus to the cytoplasm for protein synthesis by ribosomes. mRNA sequences can be designed to encode specific proteins; the ...
Bio & Medicine
Nov 10, 2022
0
30
A team of scientists at University of Oxford have worked with multiple techniques at Diamond Light Source, to solve the structure of the influenza replication machinery and to determine how it interacts with cellular proteins. ...
Cell & Microbiology
Nov 4, 2022
0
54
In an article published in the journal RNA, Karan Bedi, a bioinformatician in Mats Ljungman's lab, Department of Radiation Oncology at the University of Michigan Medical School, investigated the efficiency of splicing across ...
Biotechnology
Jul 9, 2021
0
8
Trypanosomatids are single-cell parasites that cause major diseases, such as sleeping sickness and Rose of Jericho, which affect millions of people. Trypanosoma parasites are transmitted to mammals by the blood-sucking tsetse ...
Cell & Microbiology
Mar 17, 2021
0
43
Due to the COVID 19 pandemic and the associated intensive search for therapeutics and vaccines, the chemical substance class of nucleosides is experiencing an enormous increase in interest. Natural and synthetic nucleosides ...
Biochemistry
Dec 15, 2020
0
26
A large-scale study conducted by molecular biologists from Heidelberg University has yielded groundbreaking new insights into the evolution and regulation of gene expression in mammalian organs. The scientists investigated ...
Evolution
Nov 11, 2020
2
603
Researchers have developed the first computational model of a human cell and simulated its behavior for 15 minutes—the longest time achieved for a biological system of this complexity. In a new study, simulations reveal ...
Molecular & Computational biology
Mar 25, 2020
1
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