The single-stranded genetic material RNA is best known for guiding the assembly of proteins in our cells and carrying the genetic code for viruses like SARS-CoV-2 and HIV. But 40 years ago, scientists discovered another hidden ...
Molecular & Computational biology
Aug 12, 2021
0
143
Using a specialized protein, all bacteria are capable of rapidly and effectively repairing damage to their DNA from UV. However, this mutation frequency decline (Mfd) protein plays another role and causes mutations. A team1 ...
Cell & Microbiology
Apr 7, 2021
0
139
A study done by Ludwig-Maximilians-Universitaet (LMU) in Munich physicists demonstrates that fundamental characteristics of mopolymeric lecules, such as their subunit composition, are sufficient to trigger selection processes ...
Evolution
Feb 19, 2021
46
4321
Antisense oligonucleotides (ASO) hold great promise for pharmacotherapy. Now, researchers at Tokyo Medical and Dental University (TMDU) and Ionis Pharmaceuticals, advancing their earlier work on a heteroduplex oligonucleotide ...
Biotechnology
Jan 5, 2021
0
44
Chemical reactions driven by the geological conditions on the early Earth might have led to the prebiotic evolution of self-replicating molecules. Scientists at Ludwig-Maximilians Universitaet (LMU) in Munich now report on ...
Biochemistry
Aug 7, 2020
1
397
Researchers with an interest in unraveling gene regulation in human health and disease are expanding their horizons by closely looking at alternative polyadenylation (APA), an under-charted mechanism that regulates gene expression.
Other
Jul 23, 2020
0
4
Researchers at Johns Hopkins Bloomberg School of Public Health have discovered a fundamental mechanism that regulates gene activity in cells. The newly discovered mechanism targets RNA, or ribonucleic acid, a close cousin ...
Biotechnology
Feb 3, 2020
0
76
DNA may have appeared on Earth earlier than has hitherto been assumed. LMU chemists led by Oliver Trapp show that a simple reaction pathway could have given rise to DNA subunits on the early Earth.
Biochemistry
Jun 18, 2019
0
8
A study headed by the Institute for Research in Biomedicine (IRB Barcelona) and published in the journal CHEM furthers the understanding of the asymmetry between nucleic acid hybrids. This advance may make a significant contribution ...
Biochemistry
Jun 13, 2019
0
4
RNA sequencing is a technique used to analyze entire genomes by looking at the expression of their genes. Today, such genome-wide expression analyses are a standard tool for genomic studies because they rely on high-throughput ...
Biotechnology
Apr 19, 2019
0
104
