During each cell division, more than 3.3 billion base pairs of genomic DNA have to be duplicated and segregated accurately to daughter cells. But what happens when the DNA template is damaged in such a way that the replication ...
Biotechnology
May 4, 2015
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(Phys.org)—Biologist Rami Pugatch of Princeton's Simons Center for Systems Biology has characterized the self-replication process of Escherichia coli according to a scheduling policy model derived from industrial processes. ...
Scientists have shed light on how naturally occurring mutations can be introduced into our DNA.
Biotechnology
Jan 27, 2015
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The proteins that drive DNA replication—the force behind cellular growth and reproduction—are some of the most complex machines on Earth. The multistep replication process involves hundreds of atomic-scale moving parts ...
Cell & Microbiology
Oct 15, 2014
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A new theoretical framework outlined by a Harvard scientist could help solve the mystery of how bacterial cells coordinate processes that are critical to cellular division, such as DNA replication, and how bacteria know when ...
Cell & Microbiology
Jul 15, 2014
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A group from the University of Geneva, Switzerland, discovers a key factor that curbs the undesirable triggering of DNA replication.
Cell & Microbiology
Mar 27, 2014
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(Phys.org) —A team of scientists at the Friedrich Miescher Institute for Biomedical Research and the University of Geneva has functionally dissected the molecular processes that ensure the stability of chromosomes. They ...
Cell & Microbiology
Jun 5, 2013
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(Phys.org) —For the first time, an elusive step in the process of human DNA replication has been demystified by scientists at Penn State University. According to senior author Stephen J. Benkovic, an Evan Pugh Professor ...
Cell & Microbiology
Apr 1, 2013
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For humans to grow and to replace and heal damaged tissues, the body's cells must continually reproduce, a process known as "cell division," by which one cell becomes two, two become four, and so on. A key question of biomedical ...
Biotechnology
Dec 20, 2012
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1
DNA lesions are really common —about one million individual molecular lesions per cell per day— because its long strands usually have one missing base or are damaged. These lesions can stall the DNA replication process, ...
Cell & Microbiology
Dec 3, 2012
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