Humans share over 90% of their DNA with their primate cousins. The expression or activity patterns of genes differ across species in ways that help explain each species' distinct biology and behavior.
Biotechnology
Nov 6, 2012
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0
Over the last 60 years, scientists have been able to observe how and when genetic information was replicated, determining the existence a "replication timing program," a process that controls when and in what order segments ...
Molecular & Computational biology
Apr 23, 2021
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1241
Newly developed artificial intelligence (AI) programs have accurately predicted the role of DNA's regulatory elements and three-dimensional (3D) structure based solely on its raw sequence, according to two recent studies ...
Biotechnology
Aug 8, 2022
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1110
Your DNA holds the blueprint to build your body, but it's a living document: Adjustments to the design can be made by epigenetic marks.
Molecular & Computational biology
Feb 28, 2022
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1748
Researchers at University of California San Diego have produced a single-cell chromatin atlas for the human genome. Chromatin is a complex of DNA and protein found in eukaryotic cells; regions of chromatin at key gene regulatory ...
Molecular & Computational biology
Nov 12, 2021
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304
Environment is not the only factor in shaping regulatory patterns—and it might not even be the primary factor, according to a new Rice University study that looks at how cells' protein networks relate to a bacteria's genome.
Cell & Microbiology
May 21, 2013
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0
Researchers at the MRC Weatherall Institute of Molecular Medicine's Laboratory of Gene Regulation, led by Professor Doug Higgs and Dr. Mira Kassouf, have published a study in the journal Cell, in which they reveal another ...
Cell & Microbiology
Dec 14, 2023
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131
Over the past 530 million years, the vertebrate lineage branched out from a primitive jawless fish wriggling through Cambrian seas to encompass all the diverse forms of fish, birds, reptiles, amphibians, and mammals. Now ...
Biotechnology
Aug 18, 2011
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0
A key epigenetic mark can block the binding of an important gene regulatory protein, and therefore prohibit the gene from being turned off, a new UNSW study in CRISPR-modified mice—published this month in Nature Communications—has ...
Biotechnology
May 25, 2020
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380
A new study in Science from Karolinska Institutet maps out how different DNA-binding proteins in human cells react to certain biochemical modifications of the DNA molecule. The scientists report that some 'master' regulatory ...
Biotechnology
May 4, 2017
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