Using a promiscuous inhibitor to uncover cancer drug targets

Scientists at Harvard Medical School and the Dana-Farber Cancer Institute have developed a method that exploits the multitargeted nature of a chemical inhibitor to pinpoint vulnerabilities within cancer cells.

How viruses outsmart their host cells

Viruses depend on host cells for replication, but how does a virus induce its host to transcribe its own genetic information alongside that of the virus, thus producing daughter viruses? For decades, researchers have been ...

Directed evolution builds nanoparticles

The 2018 Nobel Prize in Chemistry went to three scientists who developed the method that forever changed protein engineering: directed evolution. Mimicking natural evolution, directed evolution guides the synthesis of proteins ...

Researchers find the immune system's unknown messenger

Researchers can now explain how a cell that is being attacked by bacteria or viruses specifically manages to 'sound the alarm' among its neighbouring cells so they can react with a quick response.

Light-induced changes in photosensory proteins

Researchers from Charité - Universitätsmedizin Berlin have demonstrated on a molecular level how a specific protein allows light signals to be converted into cellular information. Their findings have broadened the understanding ...

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