News tagged with p53 tumor suppressor

A chaperone for the 'guardian of the genome'

The protein p53 plays an essential role in the prevention of cancer by initiating the controlled death of a cell with damaged genes which is in danger to transform into a cancerous cell. The heat shock protein Hsp90, in turn, ...

Sep 07, 2011
5 / 5 (3) 0 | with audio podcast

Novel compound selectively kills cancer cells

A cancer cell may seem out of control, growing wildly and breaking all the rules of orderly cell life and death. But amid the seeming chaos there is a balance between a cancer cell's revved-up metabolism and skyrocketing ...

Jul 13, 2011
4.9 / 5 (9) 1 | with audio podcast

Eggs' quality control mechanism explained

To protect the health of future generations, body keeps a careful watch on its precious and limited supply of eggs. That's done through a key quality control process in oocytes (the immature eggs), which ensures elimination ...

Feb 17, 2011
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Cancer cell survival is not 'miR-ly' dependent on p53

Squamous cell carcinoma (SCC) is a common type of skin cancer. In this paper, Leif Ellisen and colleagues at Mass General Hospital investigated the p53-related proteins p63 and p73 in SCC cells, and discovered a feedback ...

Jan 10, 2011
5 / 5 (1) 0