Nuclear pore complexes harbor new class of gene regulators

Nuclear pore complexes are best known as the communication channels that regulate the passage of all molecules to and from a cell's nucleus. Researchers at the Salk Institute for Biological Studies, however, have shown that ...

New research supports model for nuclear pore complex

(PhysOrg.com) -- To protect their DNA, cells in higher organisms are very choosy about what they allow in and out of their nuclei, where the genes reside. Guarding access is the job of transport machines called nuclear pore ...

An atomic-level look at an HIV accomplice

(PhysOrg.com) -- Since the discovery in 2007 that a component of human semen called SEVI boosts infectivity of the virus that causes AIDS, researchers have been trying to learn more about SEVI and how it works, in hopes of ...

Putting the squeeze on a cell's nucleus

Nuclear membranes protect genes—life's most precious cargo—but little is known about why they function in different tissue types. For instance, nuclei in brain cells tend to be soft and pliable while those in bone cells ...

Organizing a cell's genetic material from the sidelines

A tremendous amount of genetic material must be packed into the nucleus of every cell—a tiny compartment. One of the biggest challenges in biology is to understand how certain regions of this highly packaged DNA can be ...

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