A new study, led by researchers from the University of California, Irvine and the University of California, San Diego, reveals a new computation-guided approach to identify small molecules that can restore aspects of wild-type ...
Biochemistry
Aug 10, 2022
0
59
Urinary tract infections are common, yet are increasingly tough to treat because the bacteria that cause them are becoming resistant to many antibiotics. Now, in ACS Central Science, researchers report a new molecule that ...
Molecular & Computational biology
Aug 10, 2022
1
187
Chemists from Scripps Research and the University of California, Los Angeles, have developed methods for the precise, flexible modification of a broad class of chemical compounds called bicyclic aza-arenes, which are commonly ...
Biochemistry
Aug 9, 2022
0
313
A new technique that can analyze how drug molecules bind to proteins in tissue samples could offer an improved route to drug discovery and development.
Biochemistry
Jul 14, 2022
0
18
Using a new method, scientists are better able to distinguish between mirror-image substances. This is important amongst others in drug development, because the two variants can cause completely different effects in the human ...
Optics & Photonics
Jul 5, 2022
0
23
The chemical industry has only scratched the surface of possible molecules that could be used as drugs, which is unimaginably greater than the number of stars in the universe. To make navigating this vast chemical space more ...
Other
Jun 30, 2022
0
12
Researchers at Karolinska Institutet and SciLifeLab in Sweden describe in a study published in Science how they have improved the ability of a protein to repair oxidative DNA damage and created a new protein function. Their ...
Biochemistry
Jun 23, 2022
0
61
Proteins are like machines. For some diseases, it can be useful to turn these machine off or on when they are too active or not active enough. One way to control switching in a protein, such as a nuclear receptor, is to put ...
Molecular & Computational biology
Jun 1, 2022
0
5
Chemists at Scripps Research have unveiled a method for turning cheap and widely available chemicals known as dicarboxylic acids into potentially very valuable molecules called lactones.
Materials Science
May 27, 2022
0
125
We live in a world made and run by RNA, the equally important sibling of the genetic molecule DNA. In fact, evolutionary biologists hypothesize that RNA existed and self-replicated even before the appearance of DNA and the ...
Bio & Medicine
May 2, 2022
0
1882
