Johns Hopkins scientists have discovered a new mode of action for enzymes immersed in cellular membranes. Their experiments suggest that instead of recognizing and clipping proteins based on sequences of amino acids, these ...
Cell & Microbiology
Nov 16, 2012
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(Phys.org)—Understanding why proteins interact with certain specific molecules and not with the myriad others in their environment is a major goal of molecular biology. Now, in a series of recent papers, researchers describe ...
Biochemistry
Oct 2, 2012
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(Phys.org)—The Nanotechnology Innovation Station of the National Institute for Materials Science has succeeded in development of a technology which utilizes nanoparticles to enhance the action of immunity activating nucleic ...
Bio & Medicine
Aug 23, 2012
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Historically, fly and human Polycomb proteins were considered textbook exemplars of transcriptional repressors, or proteins that silence the process by which DNA gives rise to new proteins. Now, work by a team of researchers ...
Cell & Microbiology
Apr 30, 2012
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(PhysOrg.com) -- A compound found in red wine, grapes and other fruits, and similar in structure to resveratrol, is able to block cellular processes that allow fat cells to develop, opening a door to a potential method to ...
Biochemistry
Apr 4, 2012
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Researchers at the University of Illinois at Chicago College of Medicine describe for the first time a key target of DNA damage checkpoint enzymes that must be chemically modified to enable stable maintenance of chromosome ...
Cell & Microbiology
Nov 23, 2011
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Researchers from the Max Planck Institute of Biophysics in Frankfurt, and Mount Sinai School of Medicine in New York have provided the first atomic-level glimpse of the proton-driven motor from a major group of ATP synthases, ...
Biochemistry
Aug 3, 2010
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(PhysOrg.com) -- In the binding pockets of enzymes their natural binding partners fit exactly. The principle by which many pharmacological agents work also relies on the fact that these substances fit exactly into the pockets ...
Biochemistry
Oct 29, 2009
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BOSTON--By combining the art of origami with nanotechnology, Dana-Farber Cancer Institute researchers have folded sheets of DNA into multilayered objects with dimensions thousands of times smaller than the thickness of a ...
Biochemistry
May 20, 2009
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In three new studies — including one appearing online today in the Public Library of Science - Biology (PLoS - Biology) — UC Davis researchers provide compelling evidence of how low levels of polychlorinated biphenyls ...
Cell & Microbiology
Apr 14, 2009
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