EMBL scientists have developed a new variant of the so-called Sleeping Beauty transposase. It has dramatically improved biochemical features, including enhanced stability and intrinsic cell penetrating properties. This transposase ...
Biotechnology
Nov 4, 2019
0
23
A team from the Broad Institute of MIT and Harvard has developed a new CRISPR genome-editing approach by combining two of the most important proteins in molecular biology—CRISPR-Cas9 and a reverse transcriptase—into a ...
Biotechnology
Oct 21, 2019
2
339
Scientists routinely use genetic screens to perturb, or change the activity of, genes in mammalian cells, one at a time, to learn what those genes do. Pooled screens take this same approach but typically involve many more ...
Molecular & Computational biology
Oct 18, 2019
0
34
Deoxyribonucleic acid (DNA), is the macromolecule that holds all hereditary and genetic information. Continuously under assault, alterations and damage to DNA can lead to many different health issues, including cancer. DNA ...
Cell & Microbiology
Oct 2, 2019
0
11
Cell motility, the spontaneous movement of cells from one location to another, plays a fundamental role in many biological processes, including immune responses and metastasis. Recent physics studies have gathered new evidence ...
Wake Forest Institute for Regenerative Medicine scientists have fine-tuned their delivery system to deliver a DNA editing tool to alter DNA sequences and modify gene function. The improved "hit and run" system works faster ...
Biotechnology
Sep 13, 2019
3
183
A class of biomaterials called bulk metallic glasses could transform future implanted medical devices and other engineered objects.
Materials Science
Aug 7, 2019
0
7
Biomedical engineers at Penn State have developed a process to build protective, synthetic plant cell walls around animal cells. The work, published in Nature Communications, could hold significant potential for a variety ...
Cell & Microbiology
Jul 17, 2019
0
31
Mineralization is mediated by osteoblasts, which secrete mineral precursors through matrix vesicles (MVs) as a fundamental process in vertebrates. The vesicles are calcium and phosphate rich, containing organic materials ...
UNC School of Medicine scientists created a powerful new "directed evolution" technique for the rapid development of scientific tools and new treatments for many diseases.
Molecular & Computational biology
Jul 4, 2019
0
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