Worm genes KO'd

Knocking genes out of action allows researchers to learn what genes do by seeing what goes wrong without them. University of Utah biologists pioneered the field. Mario Capecchi won a Nobel Prize for developing knockout mice. ...

Clamshell-shaped protein puts the 'jump' in 'jumping genes'

Scientists at Johns Hopkins report they have deciphered the structure and unusual shape of a bacterial protein that prepares segments of DNA for the insertion of so-called jumping genes. The clamshell shape, they say, has ...

Jumping gene enabled key step in corn domestication

Corn split off from its closest relative teosinte, a wild Mexican grass, about 10,000 years ago thanks to the breeding efforts of early Mexican farmers. Today it's hard to tell that the two plants were ever close kin: Corn ...

Watching 'jumping genes' in action

"Jumping genes" are ubiquitous. Every domain of life hosts these sequences of DNA that can "jump" from one position to another along a chromosome; in fact, nearly half the human genome is made up of jumping genes. Depending ...

DNA protection, inch by inch

DNA within reproductive cells is protected through a clever system of find and destroy: new research published in Cell Reports today lifts the veil on how this is done.

Rare form of active 'jumping genes' found in mammals

Much of the DNA that makes up our genomes can be traced back to strange rogue sequences known as transposable elements, or jumping genes, which are largely idle in mammals. But Johns Hopkins researchers report they have identified ...

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