Study describes new way of generating insulin-producing cells

Researchers at Karolinska Institutet in Sweden show how a molecule that they have identified stimulates the formation of new insulin-producing cells in zebrafish and mammalian tissue, through a newly described mechanism for ...

Pop-up factories beneath the cell membrane

A living cell is exposed to a variety of stimuli. Countless messengers dock on its surface, where receptors in the cell membrane receive the incoming "orders." Signaling cascades are then triggered inside the cell, which ...

A genetic change for achieving a long and healthy life

Living a long, healthy life is everyone's wish, but it is not an easy one to achieve. Many aging studies are developing strategies to increase health spans, the period of life spent with good health, without chronic diseases ...

New biomarker for severe COVID-19

During the pandemic, it has become evident that people with cardiovascular disease and obesity are at much higher risk of developing very severe, even fatal COVID-19 disease. Researchers at Karolinska Institutet have identified ...

Controlling carbs and fat: Learning from the fruit fly

Incretins are hormones secreted by intestinal cells that regulate pancreatic insulin and glucagon to control sugar metabolism in mammals. Although counterparts of insulin and glucagon have been identified in invertebrates, ...

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