Most proteins have a single 'correct' way to fold; typically, improperly folded proteins are promptly eliminated by cells. However, certain misfolded proteins have a tendency to aggregate in dense fibrous clumps known as ...
Cell & Microbiology
Oct 5, 2012
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(Phys.org) -- Researchers are studying how components of cell structure function in order to determine viable ways to use them for fighting such ailments as cancer, Huntington’s, Alzheimer’s, and Parkinson’s ...
Cell & Microbiology
Jul 26, 2012
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Scientists at the Gladstone Institutes have discovered how a form of the protein linked to Huntington's disease influences the timing and severity of its symptoms, offering new avenues for treating not only this disease, ...
Biochemistry
Oct 30, 2011
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UT Southwestern Medical Center researchers have identified compounds that appear to inhibit a signaling pathway in Huntington's disease, a finding that may eventually lead to a potential drug therapy to help slow the progression ...
Biochemistry
Jun 23, 2011
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(Medical Xpress) -- McMaster researchers have discovered a new drug target that may be effective at preventing the onset of Huntington's disease, working much the same way heart medications slow the progression of heart disease ...
Biochemistry
May 31, 2011
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Hope for new ways of treating devastating neurodegenerative disorders such as Huntington's disease has been raised by a trans-Atlantic team of researchers thanks to the use of cutting-edge genetic techniques.
Biochemistry
Jan 10, 2011
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Australian scientists have identified the behaviour of the mutant protein 'huntingtin' which leads to the fatal Huntington's disease providing potential targets to treat the disease, a University of Melbourne study reveals.
Biochemistry
Jul 28, 2010
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Researchers at the University of Kentucky Markey Cancer Center and Graduate Center for Toxicology (GCT) have gained new insight into the genetic mechanisms underlying Huntington's disease and other neurodegenerative or neuromuscular ...
Cell & Microbiology
Jul 13, 2009
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Researchers from the University of Southern California have taken an important first step toward protecting against Huntington disease using gene therapy.
Biochemistry
Apr 20, 2009
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In a paper published in the early online version of Nature Structural and Molecular Biology, researchers at the University of Pittsburgh School of Medicine deconstruct the first steps in an intricate molecular dance that ...
Cell & Microbiology
Mar 8, 2009
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