A genetic change in our ancient ancestors may partly explain why humans don't have tails like monkeys, finds a new study led by researchers at NYU Grossman School of Medicine.
Evolution
Feb 28, 2024
4
65
When the human genome was first sequenced, experts predicted they would find about 100,000 genes. The actual number has turned out to be closer to 20,000, just a few thousand more than fruit flies have. The question logically ...
Cell & Microbiology
Dec 31, 2014
107
0
A Purdue University research team has revealed complex new details about the function of a key protein shared by mammals, including humans. Many cancers result when this DNA methyltransferase protein goes awry.
Cell & Microbiology
Aug 23, 2023
0
1
In a development that could accelerate the discovery of new diagnostics and treatments, researchers at Children's Hospital of Philadelphia (CHOP) have developed a versatile and low-cost technology for targeted sequencing ...
Molecular & Computational biology
Aug 15, 2023
0
54
A major puzzle of biology is that while the human genome contains roughly 20,000 genes, many comparatively primitive organisms—including the universally-studied worm C. elegans—have almost the same number of genes.
Biotechnology
Mar 23, 2023
1
133
On the journey from gene to protein, a nascent RNA molecule can be cut and joined, or spliced, in different ways before being translated into a protein. This process, known as alternative splicing, allows a single gene to ...
Molecular & Computational biology
Jan 20, 2023
1
168
Researchers at the Centre for Genomic Regulation (CRG) in Barcelona reveal that Srrm3 is a master regulator gene crucial for the development of photoreceptors, cells in the back of the retina which capture and process light, ...
Cell & Microbiology
Jul 13, 2022
0
23
A research team at Children's Hospital of Philadelphia (CHOP) has developed an innovative computational tool offering researchers an efficient method for detecting the different ways RNA is pieced together (spliced) when ...
Molecular & Computational biology
Mar 25, 2019
0
204
It's well known that when the DNA in a cell is damaged, the cell responds by activating specific genes that help defend the integrity of its genome. But less well studied is the fact that the cell actually shuts down the ...
Cell & Microbiology
Feb 17, 2017
0
14
RNA splicing is a major underlying factor that links mutations to complex traits and diseases, according to an exhaustive analysis of gene expression in whole genome and cell line data. Reporting in Science on April 29, 2016 ...
Cell & Microbiology
Apr 28, 2016
0
25
