By creating a powerful new gene regulation system called CRISPR-on, Whitehead Institute researchers now have the ability to increase the expression of multiple genes simultaneously and precisely manipulate each gene's expression ...
Biotechnology
Aug 27, 2013
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German researchers have demonstrated for the first time why the molecular cocktail responsible for generating stem cells works. Sox2 and Oct4 are proteins whose effect on cells resembles that of an eraser: They remove all ...
Cell & Microbiology
Aug 19, 2013
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(Phys.org) —Jonathan Tang had a problem. A graduate student studying neural circuitry in the retina, he wanted to do more than identify fluorescent cells that send signals to the brain. He sought to understand how these ...
Biotechnology
Aug 16, 2013
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A decade ago, gene expression seemed so straightforward: genes were either switched on or off. Not both. Then in 2006, a blockbuster finding reported that developmentally regulated genes in mouse embryonic stem cells can ...
Cell & Microbiology
Aug 11, 2013
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Scientists at the Friedrich Miescher Institute for Biomedical Research have identified a novel and unexpected regulatory activity of RNA at the edge of inactive chromosomal regions. In their publication in Nature Structural ...
Cell & Microbiology
Aug 8, 2013
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(Phys.org) —New research by academics at The University of Nottingham has shown that exposure to a neonicotinoid insecticide causes changes to the genes of the honeybee.
Plants & Animals
Jul 2, 2013
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In nearly every organism's genome, scattered between genes that encode proteins, long regulatory regions stretch across expanses of DNA. Understanding what role these so-called enhancer regions play in controlling the activation ...
Biotechnology
Jul 1, 2013
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What allows certain plants to survive freezing and thrive in the Canadian climate, while others are sensitive to the slightest drop in temperature? Those that flourish activate specific genes at just the right time—but ...
Biotechnology
Jun 30, 2013
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What makes one Argonaute a slicer and another one not? Human Argonaute proteins are key players in the gene regulation process known as RNA interference, RNAi. Professor Joshua-Tor's group of Cold Spring Harbor Laboratory ...
Cell & Microbiology
Jun 6, 2013
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Scientists have found an entirely new genetic route by which a now-banned chemical causes sexual and hormonal disruption in a marine mollusc.
Ecology
May 23, 2013
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