Glutathione S-transferases (GST) is one of the most important phase II detoxification enzymes. It achieves detoxification by catalyzing the nucleophilic attack of glutathione (GSH) on the electrophilic center of the target ...
Materials Science
Oct 29, 2020
0
2
For those not involved in chemistry or biology, picturing a cell likely brings to mind several discrete, blob-shaped objects; maybe the nucleus, mitochondria, ribosomes and the like.
Bio & Medicine
Aug 25, 2020
0
218
There is an ongoing demand in biological research to accelerate the development of fluorescent probes based on the photo-induced electron transfer (PET) mechanism. By modulating PET formations, these probes significantly ...
Materials Science
May 14, 2020
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26
Genes are like instructions, but with options for building more than one thing. Daniel Larson, senior investigator at the National Cancer Institute, studies this gene "splicing" process, which happens in normal cells and ...
Molecular & Computational biology
Feb 18, 2020
0
5
Selecting the most effective molecules for drug delivery is often a trial-and-error process, but Cornell engineers are providing some precision thanks to a technique that reveals the performance of those molecules inside ...
Biochemistry
Nov 2, 2019
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123
Antibodies are the biomolecules our immune systems deploy to find, tag and destroy invading pathogens. They work by binding to specific targets, called epitopes, on the surfaces of antigens—like locks to keys.
Molecular & Computational biology
Jul 3, 2019
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4
Part of the immune system in the brain is made up of so-called microglia cells. Korean and Singaporean researchers have now developed a fluorescent probe that specifically labels this type of macrophage. The cells were visualized ...
Materials Science
May 16, 2019
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5
Researchers at Karolinska Institutet present a publicly available resource that can accelerate the use of so-called FISH techniques for studying how the genome is spatially organised in the cell nucleus. The new platform, ...
Biotechnology
Apr 12, 2019
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94
Ethylene is a gaseous plant hormone which regulates a wide range of biological processes in plants. It is associated with the ripening processes in a number of fruits such as apples and pears. Better understanding of the ...
Materials Science
Mar 26, 2019
0
13
In everyday life, blinking lights can send signals—for example, that a car is going to turn. Now, researchers have engineered tiny "blinkers" that reveal single molecules of RNA or protein inside cells based on the duration ...
Nanomaterials
Mar 13, 2019
0
52
