Understanding the APJ Receptor Binding Site

(PhysOrg.com) -- Apelin is a recently discovered peptide that binds to the apelin (or APJ) G-protein-coupled receptor. Apelin-13 (NH2-QRPRLSHKGPMPF-COOH), one of several cleavage products of the proprotein form of the apelin ...

New research increases understanding of drug metabolism

Research led by Wayne L. Backes, PhD, Professor of Pharmacology and Associate Dean for Research at LSU Health Sciences Center New Orleans School of Medicine, has found that drug metabolism depends not only upon which enzymes ...

'Fatostatin' is a turnoff for fat genes

A small molecule earlier found to have both anti-fat and anti-cancer abilities works as a literal turnoff for fat-making genes, according to a new report in the August 28th issue of the journal Chemistry and Biology, a Cell ...

Chip simulates metabolism of medicine in human body

(PhysOrg.com) -- A tiny electrochemical cell, developed by researchers of the MESA+ Institute for Nanotechnology, The Netherlands, is able to mimick the behaviour of medicine inside a human body. This chip is presented in ...

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