A recent study published in Nature Biotechnology revealed the development of high-fidelity Cas13 variants with markedly reduced collateral effects by mutagenesis and demonstrated the feasibility of hfCas13 for efficient on-target ...
Biotechnology
Aug 12, 2022
0
11
DNA damage caused by factors such as ultraviolet radiation affect nearly three-quarters of all stem cell lines derived from human skin cells, say Cambridge researchers, who argue that whole genome sequencing is essential ...
Molecular & Computational biology
Aug 11, 2022
0
240
CRISPR/Cas9 is a precise gene editing technique whose development by Jennifer A. Doudna and Emmanuelle Charpentier was recognized with the 2020 Nobel Prize in Chemistry. Commonly known as "genetic scissors," CRISPR allows ...
Biotechnology
Aug 9, 2022
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3005
Epithelial cells, which line the surfaces and organs of the body, can protect themselves against cancer by removing unhealthy or abnormal cells through a mechanism known as "apical extrusion," where the damaged cells are ...
Cell & Microbiology
Jul 11, 2022
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62
The Wake Forest Institute for Regenerative Medicine (WFIRM) researchers, who were the first to identify that stem cells in human urine have potential for tissue regenerative effects, continue their investigation into the ...
Cell & Microbiology
Jun 28, 2022
2
687
Ethyl carbamate (EC) is a hazardous substance naturally produced during the fermentation of food and beverages. It has been categorized as probably carcinogenic to humans (Group 2A) by the World Health Organization's International ...
Biochemistry
Jun 16, 2022
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18
Recent work from Carnegie's Chenhui Wang and Allan Spradling reveals a surprising capability of renal stem cells in fruit flies—remodeling. Their work, which could eventually guide kidney stone treatments, was published ...
Cell & Microbiology
Jun 16, 2022
0
22
Testicles of most mammals are cooled in the scrota, and elevated testicular temperatures lead to spermatogenesis failure and male infertility. A research team led by Shosei Yoshida at the National Institute for Basic Biology ...
Cell & Microbiology
May 26, 2022
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26
Researchers from the Microbeam Technology and Applications Group at the Institute of Modern Physics (IMP) of the Chinese Academy of Sciences (CAS) have discovered the high turnover and rescue effect of an important scaffold ...
Molecular & Computational biology
May 20, 2022
0
27
The brain is the organ that orchestrates all the diverse functions and complex decisions that take place in biological systems. Despite its critical nature, it is equally as fragile: the neurons that make up the brain do ...
Plants & Animals
Apr 27, 2022
0
76
