Study of Arctic fishes reveals the birth of a gene—from 'junk'

Though separated by a world of ocean, and unrelated to each other, two fish groups—one in the Arctic, the other in the Antarctic—share a surprising survival strategy: They both have evolved the ability to produce the ...

CRISPR-based tool maps gene function in human cells

UC San Francisco scientists have used a high-throughput CRISPR-based technique to rapidly map the functions of nearly 500 genes in human cells, many of them never before studied in detail.

The cartography of the nucleus

Nestled deep in each of your cells is what seems like a magic trick: Six feet of DNA is packaged into a tiny space 50 times smaller than the width of a human hair. Like a long, thin string of genetic spaghetti, this DNA blueprint ...

Mathematical analysis reveals architecture of the human genome

Mathematical analysis has led researchers in Japan to a formula that can describe the movement of DNA inside living human cells. Using these calculations, researchers may be able to reveal the 3D architecture of the human ...

Barcodes to identify gene regulators

The same DNA is present in every cell of an organism, but only some genes are expressed in a given cell. These genes are activated by proteins called transcription factors, in response to various biological signals. Transcription ...

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