Simulations open a new way to reverse cell aging

Research findings by a KAIST team provide insight into the complex mechanism of cellular senescence and present a potential therapeutic strategy for reducing age-related diseases associated with the accumulation of senescent ...

Aging cells lose their grip on DNA rogues

(Phys.org)—Transposable elements are mobile strands of DNA that insert themselves into chromosomes with mostly harmful consequences. Cells try to keep them locked down, but in a new study, Brown University researchers ...

Damage to cell membranes causes cell aging, finds new study

Our cells are surrounded by a fragile membrane that's only 5 nanometers thick, 1/20 of a soap bubble. Cells are easily damaged by physiological activities, including muscle contraction and tissue injury. To cope with such ...

Aging cells unravel their DNA

Senescent cells, which are metabolically active but no longer capable of dividing, contribute to aging, and senescence is a key mechanism for preventing the spread of cancer cells. A study in The Journal of Cell Biology identifies ...

Scientists boost lifespan of mice by deleting defective cells

The ageing population is one of the greatest challenges facing society. More people are surviving to old age than ever before, but we currently lack the means to keep them healthy and independent. If a treatment existed to ...

Cellular aging: A basic paradox elucidated

In a study published in Nucleic Acids Research, the team of cancer researcher Francis Rodier, an Université de Montréal professor, shows for the first time that cellular senescence, which occurs when aging cells stop dividing, ...

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