For the first time, scientists at Fred Hutchinson Cancer Research Center have defined key events that take place early in the process of cellular aging.
Nov 21, 2012
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One of the few reliable ways to extend an organism's lifespan, be it a fruit fly or a mouse, is to restrict calorie intake. Now, a new study in fruit flies is helping to explain why such minimal diets are ...
Nov 02, 2011
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(PhysOrg.com) -- Animals who consume fewer calories live longer and healthier lives. Now, a seminal study at the University of California, San Francisco is testing whether the same is true for extreme dieters.
Apr 19, 2011
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When mice are given drinking water laced with a special concoction of amino acids, they live longer than your average mouse, according to a new report in the October issue of Cell Metabolism. The key ingredients in the su ...
Oct 05, 2010
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New research being presented this week is giving scientists new insight into why a restricted diet can lead to a longer lifespan and reduced incidence of age-related diseases for a wide variety of animals. Scientists have ...
Jul 16, 2010
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Apoptosis, the natural 'programmed' death of cells, is arrested in the aftermath of strenuous exercise. Researchers writing in the open access journal BMC Physiology studied peripheral blood mononuclear cells (PBMCs), isolat ...
May 11, 2010
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Scientists funded by the Agricultural Research Service (ARS) found that volunteers who followed a low-calorie diet or a very low-calorie diet not only lost weight, but also significantly enhanced their immune response. The ...
Apr 29, 2010
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Organisms from yeast to rodents to humans all benefit from cutting calories. In less complex organisms, restricting calories can double or even triple lifespan. It's not yet clear just how much longer calorie restriction ...
Apr 15, 2010
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While there are many benefits of losing weight, weight reduction also might negatively affect bones in the body. During weight loss, bones are being remodeled - breaking down old bone and forming new bone ...
Mar 11, 2010
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(PhysOrg.com) -- A new paper from MIT biology professor Leonard Guarente strengthens the link between longevity proteins called sirtuins and the lifespan-extending effects of calorie restriction.
Dec 14, 2009
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Scientists searching for the secrets of how calorie-restricted diets increase longevity are reporting discovery of proteins in the fat cells of human volunteers that change as pounds drop off. The proteins ...
Dec 09, 2009
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Getting the correct balance of proteins in our diet may be more important for healthy ageing than reducing calories, new research funded by the Wellcome Trust and Research into Ageing suggests.
Dec 02, 2009
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Researchers at Mount Sinai School of Medicine set out to address a question that has been challenging scientists for years: How do dietary restriction—and the reverse, overconsumption—produce protective effects against ...
Nov 18, 2009
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Resveratrol, a molecule found in red grapes, has been shown to improve diabetes when delivered orally to rodents. Until now, however, little has been known about how these beneficial changes are mediated in the body. A new ...
Oct 06, 2009
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Scientists have managed to extend the lifespan of mice by up to a fifth and reduce the number of age-related diseases the animals suffer. The research, which involved blocking a key molecular pathway, mimics ...
Oct 01, 2009
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