As many know, females have two X chromosome while males have one X and one Y chromosome.
In cell biology, men and women are unequal: men have an X chromosome, while women have two. How can we get around this difference? Geneticists from the University of Geneva (UNIGE), Switzerland, turned to some historic research ...
Scientists from the University of North Carolina School of Medicine have developed a powerful method for exploring the properties of mysterious molecules called long non-coding RNAs (lncRNAs), some of which have big roles ...
An international group of researchers have raised the viability of mice that were cloned using a method called somatic cell nuclear transfer, by stimulating two epigenetic factors, and by doing this have shown that creating ...
A Massachusetts General Hospital (MGH) research team has identified the essential role of a structural protein in the silencing of the inactive X chromosome, a process that prevents both copies of the same gene from being ...
Autoimmune diseases tend to strike women more than men and having multiple X chromosomes could be the main reason why. While a process called X chromosome inactivation serves to balance out gene dosage between males and females, ...
Researchers have discovered new insights into how one of the two X-chromosomes is silenced during the development of female human embryos and also in lab-grown stem cells. X-chromosome silencing is essential for proper development ...
The addition of a chemical tag on an RNA molecule is the critical switch that inactivates one X chromosome in every cell, ensuring healthy development in all female mammals, according to new research by Weill Cornell Medicine ...
Early in the development of female embryos, a crucial event occurs in all cells: An X chromosome is silenced. Whereas males have only one X chromosome, females have two—which means they can have twice as many proteins generated ...
Whitehead Institute scientists have created a checklist that defines the "naive" state of cultured human embryonic stem cells (ESCs). Such cells can mature into almost any cell type and more closely resemble the unique molecular ...
