A complete sequence of the human genome has finally been published by an international consortium of scientists. The new reference genome fills in many gaps that were left by earlier drafts, especially in the centromeres ...
Researchers have shown for the first time that embryonic cells destined to become either egg or sperm rely on different methods of repressive gene regulation.
Chromosomes occupy specific regions of the cell nucleus called chromosome territories. In somatic cells, scientists have observed that there is a correlation between this positioning and genome regulation. In fact, alterations ...
A large international team of researchers is claiming to have at last sequenced the entire human genome. Collectively, the team is known as the Telomere-to-Telomere (T2T) Consortium, and they have written a paper describing ...
A study led by scientists at the UAB and conducted with mice models reveals how chromosomal reorganizations alter the genome's three-dimensional organization in germ cells. The study, published in Nature Communications, opens ...
The DNA molecule is not naked in the nucleus. Instead, it is folded in a very organized way by the help of different proteins to establish a unique spatial organization of the genetic information. This 3D spatial genome organization ...
Not all species need sperm to fertilize an egg for sexual reproduction. Some species need sperm in order to induce completion of egg nucleus development, but then never use the sperm's DNA. I describe how this self-sexual ...
The Genome in a Box project is the brainchild of researchers Anthony Birnie and Cees Dekker from the Dept. of Bionanoscience at the Delft University of Technology. Their stated goal is to assemble a functioning chromosome ...
Moles roam in an extreme habitat. As mammals that burrow deep into the earth, they have forepaws with an extra finger and exceptionally strong muscles. What's more, female moles are intersexual while retaining their fertility. ...
Parents pass genes along to their offspring traits that equip them for life. In recent years, research has shown that the reality is much more complex and that parents endow much more than just genes. A new study in Cell ...
