Search results for facial malformations

Cell & Microbiology Apr 22, 2024

Pressure in the womb may influence facial development

Physical cues in the womb, and not just genetics, influence the normal development of neural crest cells, the embryonic stem cells that form facial features, finds a new study led by UCL researchers.

Molecular & Computational biology Dec 8, 2021

Embryonic cells sense stiffness in order to form the face

Cells in the developing embryo can sense the stiffness of other cells around them, which is key to them moving together to form the face and skull, finds a new study by UCL researchers.

Biotechnology Apr 8, 2021

Complete chromosome 8 sequence reveals novel genes and disease risks

The full assembly of human chromosome 8 is reported this week in Nature. While on the outside this chromosome looks typical, being neither short nor long or distinctive, its DNA content and arrangement are of interest in ...

Veterinary medicine Nov 7, 2019

New AI could help diagnose dogs suffering from chronic pain

CKCS are predisposed to CM—a disease which causes deformity of the skull, the neck (cranial cervical vertebrae) and, in some extreme cases, lead to spinal cord damage called syringomyelia (SM). While SM is straightforward ...

Plants & Animals Jan 28, 2019

Can dog show judges spot risky head shape?

Breed show judges could improve dogs' health by using their ability to detect subtle differences in head shapes of Cavalier King Charles spaniels, a new study by the School of Veterinary Science at the University of Surrey ...

Cell & Microbiology Oct 18, 2018

New cell movement process key to understanding and repairing facial malformations

The embryonic stem cells that form facial features, called neural crest cells, use an unexpected mechanism of moving from the back of the head to the front to populate the face, finds a new UCL-led study.

Cell & Microbiology Oct 10, 2017

Unexpected regulation of transcription factors critical to development

A team of developmental biologists at the University of Massachusetts Amherst led by Dominique Alfandari, with others at MIT, report in a new paper that they have for the first time described how two transcription factors ...

Cell & Microbiology Jun 15, 2017

Newly identified method of gene regulation challenges accepted science, researchers say

Researchers at the Stanford University School of Medicine have discovered an unexpected layer of the regulation of gene expression. The finding will likely disrupt scientists' understanding of how cells regulate their genes ...

Plants & Animals Aug 6, 2014

Skull shape risk factors could help in the welfare of toy dog breeds

New research has identified two significant risk factors associated with painful neurological diseases in the skull shape of the Cavalier King Charles Spaniel (CKCS). The findings could help in tackling these conditions in ...

Biotechnology Apr 3, 2014

High-tech examination of a cave-dwelling fish finds possible genetic link to human disorders

Researchers have identified a genetic association with facial asymmetry in an ancient cavefish, a natural trait that may solve mysteries surrounding facial asymmetries in humans – conditions such as cleft palate or hemifacial ...

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