The National Institutes of Health (NIH) is an agency of the United States Department of Health and Human Services and is the primary agency of the United States government responsible for biomedical and health-related research. Its science and engineering counterpart is the National Science Foundation. It comprises 27 separate institutes, centers, and offices which includes the Office of the Director. Francis S. Collins is the current Director. As of 2003, the NIH was responsible for 28%—about US$26.4 billion—of the total biomedical research funding spent annually in the U.S., with most of the rest coming from industry. The NIH's research is divided into two parts: the NIH Extramural Research Program is responsible for the funding of biomedical research outside the NIH, while the NIH Intramural Research Program (IRP) is the internal research program of the NIH, known for its synergistic approach to biomedical science. With 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, the IRP is the largest biomedical research institution on earth.
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For every cell in the body there comes a time when it must decide what it wants to do for the rest of its life. In an article published in the journal PNAS, NIH researchers report for the first time that ancient viral genes ...
Molecular & Computational biology
Jul 13, 2020
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Researchers have launched an ultra-large virtual docking library expected to grow to more than 1 billion molecules by next year. It will expand by 1000-fold the number of such "make-on-demand" compounds readily available ...
Biochemistry
Feb 6, 2019
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Imagine having superhuman hearing. You're at a noisy, cocktail party and yet your ears can detect normally inaudible sounds made by your friends' muscles as they lean in to dish the latest gossip. But, unlike normal hearing, ...
Plants & Animals
May 30, 2018
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Bioengineers have created three-dimensional brain-like tissue that functions like and has structural features similar to tissue in the rat brain and that can be kept alive in the lab for more than two months.
Biotechnology
Aug 11, 2014
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If left to their own devices, bacteria on our teeth or wounded skin can encase themselves in a slimy scaffolding, turning into what is called biofilm. These bacteria wreak havoc on our tissue and, being shielded from antibiotic ...
Bio & Medicine
Mar 13, 2024
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A new study suggests that cells preparing to divide can reverse this process and return to a resting state, challenging long-held beliefs about cell division. If interrupted early in their preparation to divide, cells were ...
Cell & Microbiology
Jul 5, 2023
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Early detection of infectious diseases can be key to successful treatment, but we often don't know we are infected until symptoms appear. What if our bodies could detect the presence of an infectious pathogen before the onset ...
Biotechnology
Jul 5, 2023
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Therapeutics that use mRNA—like some of the COVID-19 vaccines—have enormous potential for the prevention and treatment of many diseases. These therapeutics work by shuttling mRNA "instructions" into target cells, providing ...
Bio & Medicine
Apr 3, 2023
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National Institutes of Health researchers have identified a gene that makes yeast resistant to a lethal toxin, according to a new study published in the Proceedings of the National Academy of Sciences. To study the evolution ...
Cell & Microbiology
Feb 21, 2023
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42
Researchers from the National Institutes of Health have developed a three-dimensional structure that allows them to see how and where disease mutations on the twinkle protein can lead to mitochondrial diseases. The protein ...
Molecular & Computational biology
Aug 5, 2022
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