Howard Hughes Medical Institute scientists have simplified the chemical synthesis of small molecules, eliminating a major bottleneck that limits the exploration of a class of compounds offering tremendous potential for medicine ...
Biochemistry
Mar 12, 2015
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The remarkable diversity of anatomical features along the body axis of animals—the differences between the head, the thorax and the abdomen, for example—is determined by proteins in the Hox family. But almost as soon ...
Biotechnology
Jan 22, 2015
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Howard Hughes Medical Institute (HHMI) scientists have new structures of an essential cellular recycling machine that depict its structure with near atomic-level detail. The structures, which show a protein called NSF alone ...
Cell & Microbiology
Jan 13, 2015
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(Phys.org) —A dust-covered fly might spend more than 20 minutes removing the offending grit and grime from its body. With only its own legs to complete the chore, the fly needs a plan of attack. Thanks to a strategy hardwired ...
Plants & Animals
Aug 20, 2014
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Recent advances in imaging technology are transforming how scientists see the cellular universe, showing the form and movement of once grainy and blurred structures in stunning detail. But extracting the torrent of information ...
Cell & Microbiology
Jul 20, 2014
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The complexity of biology can befuddle even the most sophisticated light microscopes. Biological samples bend light in unpredictable ways, returning difficult-to-interpret information to the microscope and distorting the ...
General Physics
Apr 13, 2014
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For structural biologists, the first step in determining a protein's precise molecular structure is often the hardest: coaxing the protein to grow into the orderly, three-dimensional crystals that are the starting material ...
Biotechnology
Nov 20, 2013
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(Phys.org)—The parasites that cause schistosomiasis, one of the most common parasitic infections in the world, are notoriously long-lived. Researchers have now found stem cells inside the parasite that can regenerate worn-down ...
Cell & Microbiology
Feb 23, 2013
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(Phys.org)—The plasma membranes that give cells their shapes are typically upheld by linear meshworks of the protein actin. In contrast, Howard Hughes Medical Institute scientists have now discovered that periodic ring-shaped ...
Cell & Microbiology
Jan 28, 2013
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(Phys.org)—Every minute of its existence, a living cell must assess and analyze myriad bits of information—everything from the temperature of its environment to the chemical makeup of its surroundings. Sometimes, these ...
Cell & Microbiology
Jan 25, 2013
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