Nicotine exposure affects food response

Sep 06, 2005

Yale University researchers say nicotine exposure in mice can increase their motivation to respond to food for weeks after their last exposure to nicotine. The finding, said the scientists, runs counter to the popular belief that nicotine exposure curbs appetite and sheds new light on the role played by certain nicotinic acetylcholine receptors involved in reinforcing aspects of nicotine.

Darlene Brunzell, an associate psychiatry research scientist and first author of the study, said the findings provide insight into one of the most vexing issues relating to smoking cessation -- the prospect of weight gain.

"Although acute nicotine can act as an appetite suppressant, these data are the first to suggest repeated exposure to nicotine has the opposite effect, that nicotine increases motivation for food for weeks following exposure to the drug," she said.

Stephanie O'Malley, professor of psychiatry and principal investigator for the Center for Nicotine & Tobacco Use Research at Yale said, "More research is needed to determine how exactly that works, but this does show that there could be a connection between exposure to nicotine and subsequent weight gain in some individuals."

The findings are to be detailed in an upcoming issue of the journal Psychopharmacology.

Copyright 2005 by United Press International

Explore further: Congressional rift over environment influences public

add to favorites email to friend print save as pdf

Related Stories

The source of the sky's X-ray glow

16 hours ago

In findings that help astrophysicists understand our corner of the galaxy, an international research team has shown that the soft X-ray glow blanketing the sky comes from both inside and outside the solar system.

Vietnam's taste for cat leaves pets in peril

1 hour ago

The enduring popularity of "little tiger" as a snack to accompany a beer in Vietnam means that cat owners live in constant fear of animal snatchers, despite an official ban.

Recommended for you

Congressional rift over environment influences public

1 hour ago

American citizens are increasingly divided over the issue of environmental protection and seem to be taking their cue primarily from Congress, finds new research led by a Michigan State University scholar.

Rural loss and ruin can be avoided

4 hours ago

An Australian Reconstruction Development Board needs to be established to help avoid more needless forcing of Australian farmers from their land, a QUT economist has said.

Fragment of Ice Age ivory lion gets its head back

5 hours ago

Archaeologists from the University of Tübingen have found an ancient fragment of ivory belonging to a 40,000 year old animal figurine. Both pieces were found in the Vogelherd Cave in southwestern Germany, ...

User comments : 0