Getting DNA to self-assemble

Aug 25, 2005

University of Illinois researchers have developed new ways to get DNA to self-assemble into various kinds of structures.

The findings might help deliver genetic material to locations in the body for gene therapy or in highly targeted drug delivery, reported the Champaign (Ill.) News-Gazette Thursday.

Gerard Wong and his colleagues have been developing techniques for using positively charged ions -- calcium, magnesium and the like -- to glue negatively charged DNA and negatively charged delivery molecules to one another.

Wong said he is interested in how a similar, pathological molecular self-assembly process contributes to cystic fibrosis -- an inherited disease that thickens mucus and other bodily fluids and leads to respiratory failure.

The findings are published in the Proceedings of the National Academy of Sciences.

Copyright 2005 by United Press International

Explore further: Experts examine bones as Spain hunts for Cervantes' remains (Update)

add to favorites email to friend print save as pdf

Related Stories

Toward mitochondrial plant cell factories

Jan 15, 2015

In work published in Scientific Reports, a group of researchers led by Jo-Ann Chuah and Keiji Numata of the RIKEN Center for Sustainable Resource Science have devised a new strategy for selectively delive ...

Recommended for you

Young people overly optimistic about finances

Jan 23, 2015

A new survey of young New Zealanders by the Westpac-Massey Fin-Ed Centre shows that many believe their financial situation will improve in the coming year and their money management skills require no improvement.

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.