Molecular movies of RNA guide drug discovery
Thumb through any old science textbook, and you'll likely find RNA described as little more than a means to an end, a kind of molecular scratch paper used to construct the proteins encoded in DNA.
Thumb through any old science textbook, and you'll likely find RNA described as little more than a means to an end, a kind of molecular scratch paper used to construct the proteins encoded in DNA.
Biotechnology
May 4, 2018
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210
Double-strand breaks in DNA happen every time a cell divides and replicates. Depending on the type of cell, that can be pretty often. Many proteins are involved in everyday DNA repair, but if they are mutated, the repair ...
Cell & Microbiology
Feb 3, 2013
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The structure of an important protein complex that regulates the metaphase-to-anaphase transition during cell cycle progression has been solved using cryo-electron microscopy (cryo-EM) at Diamond Light Source. The structural ...
Biochemistry
Apr 24, 2017
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49
Over the last two decades, scientists have come to understand that the genetic code held within DNA represents only part of the blueprint of life. The rest comes from specific patterns of chemical tags that overlay the DNA ...
Biotechnology
Sep 30, 2012
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Scientists know that cells in all higher organisms cells need to bind to each other for the development, architecture, maintenance and function of tissues. Mysteries have remained, however, about exactly how cells manage ...
Cell & Microbiology
Jan 6, 2013
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By the time you reach the end of this sentence, RNA folding will have taken place in your body more than 10 quadrillion times. The folding of RNA is essential to life, yet because it happens so rapidly, researchers have difficulty ...
Biochemistry
Oct 31, 2016
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498
A key building block of life, actin is one of the most abundant and highly conserved proteins in eukaryotic cells.
Cell & Microbiology
Mar 24, 2013
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Researchers at ETH Zurich and the University of Bern have discovered a mechanism by which the corona virus manipulates human cells to ensure its own replication. This knowledge will help to develop drugs and vaccines against ...
Cell & Microbiology
Sep 14, 2020
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112
Researchers have discovered critical new details about the structure of a virus that causes potentially fatal brain swelling and paralysis in children, pointing toward designs for antiviral drugs to treat the disease.
Cell & Microbiology
Mar 2, 2012
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A cell's genome maintains its integrity by organizing some of its regions into a super-compressed form of DNA called heterochromatin. In the comparatively simple organism fission yeast, a cellular phenomenon known as RNA ...
Cell & Microbiology
Nov 13, 2011
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