New techniques to assess the fate of stem cells in vivo

Stem cells ensure the development of tissues, their daily maintenance and their repair following injuries. One of the key questions in the field of stem cell biology is to define the different cell lineages in which stem ...

Stem cells know how to open up and unwind

Research led by the Babraham Institute with collaborators in the UK, Canada and Japan has revealed a new understanding of how an open genome structure supports the long-term and unrestricted developmental potential in embryonic ...

New insight into leaf shape diversity

Many of us probably remember the punnett squares by which we were introduced to the idea of genetic inheritance in school: a dominant allele in each of my brown-eyed parents hides a recessive allele that explains my blue ...

RNA's part in determining the health of stem cells

What makes stem cells so interesting is that they are pluripotent: they have the potential to become any cell in an organism. Their ability to differentiate into any cell and be used to replace those that are damaged or ...

Cell aging slowed by putting brakes on noisy transcription

Working with yeast and worms, researchers found that incorrect gene expression is a hallmark of aged cells and that reducing such "noise" extends lifespan in these organisms. The team published their findings this month in ...

Protein plays unexpected role in embryonic stem cells

What if you found out that pieces of your front door were occasionally flying off the door frame to carry out chores around the house? That's the kind of surprise scientists at the Salk Institute experienced with their recent ...

Study shows where damaged DNA goes for repair

A Tufts University study sheds new light on the process by which DNA repair occurs within the cell. In research published in the May 15 edition of the journal Genes & Development and available May 4 online in advance of print, ...

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