ACS Synthetic Biology is a monthly peer-reviewed journal dedicated to research in synthetic biology and biological systems. Led by Editor-in-Chief Christopher A. Voigt of the Massachusetts Institute of Technology, the journal publishes high-quality research that demonstrate integrative, molecular approaches enabling better understanding of the organization and function of cells, tissues, and organisms in systems.
'Rewriting' the way to make natural drug compounds
One of the big hurdles in bringing drugs to market is the difficulty of producing large enough quantities of potential compounds to conduct clinical trials. This is particularly true with compounds made by organisms, which ...
Scientists manipulate split proteins to detect interactions in living cells
(Phys.org) —Rice University scientists have developed a plug-and-play approach to detect interactions between proteins they say could greatly improve understanding of basic biological functions.
New tools advance bio-logic: Researchers build more sophisticated synthetic gene circuits
(Phys.org) —Researchers at Rice University and the University of Kansas Medical Center are making genetic circuits that can perform more complex tasks by swapping protein building blocks.
Engineered bacteria produce biofuel alternative for high-energy rocket fuel
Researchers at the Georgia Institute of Technology and the Joint BioEnergy Institute have engineered a bacterium to synthesize pinene, a hydrocarbon produced by trees that could potentially replace high-energy ...
Genetic languages guide the design of synthetic biological systems
(Phys.org) —Researchers at Virginia Tech and the Massachusetts Institute of Technology have used a computer-aided design tool to create genetic languages to guide the design of biological systems.
Recruiting E. coli to combat hard-to-treat bacterial infections
The notorious bacteria E. coli is best known for making people sick, but scientists have reprogrammed the microbe—which also comes in harmless varieties—to make it seek out and fight other disease-causing pathog ...
Researchers engineer bacterium to hunt down and kill pathogens
New method for turning genes on and off could enable more complex synthetic biology circuits
MIT researchers have shown that they can turn genes on or off inside yeast and human cells by controlling when DNA is copied into messenger RNA—an advance that could allow scientists to better understand ...
Writing rules for gene-therapy vectors: Researchers compute, then combine benign viruses to fight disease
Rice University researchers are making strides toward a set of rules to custom-design Lego-like viral capsid proteins for gene therapy.
Fractal patterns spontaneously emerge during bacterial cell growth
Scientists discover highly asymmetric and branched patterns are the result of physical forces and local instabilities; research has important implications for understanding biofilms and multicellular systems.
Biology's drive toward engineering
Biology is on the verge of getting its versions of the lever, wheel and axle, pulley and other basic machines that enable engineers to build almost any mechanical device, a new analysis has concluded. The ...
Fast new, one-step genetic engineering technology
A new, streamlined approach to genetic engineering drastically reduces the time and effort needed to insert new genes into bacteria, the workhorses of biotechnology, scientists are reporting. Published in ...
The first caffeine-'addicted' bacteria
Some people may joke about living on caffeine, but scientists now have genetically engineered E. coli bacteria to do that—literally. Their report in the journal ACS Synthetic Biology describes bacteria bein ...
Advance in re-engineering photosynthesis to make drugs, compounds or ingredients
Scientists are reporting an advance in re-engineering photosynthesis to transform plants into bio-factories that manufacture high-value ingredients for medicines, fabrics, fuels and other products. They report ...
Advance promises to expand biological control of crop pests
A new discovery promises to allow expanded use of a mainstay biological pest control method, which avoids the health, environmental and pest-resistance concerns of traditional insecticides, scientists are reporting. The advance ...