A seldom-studied gene known as notum plays a key role in the planarian's regeneration decision-making process, according to Whitehead Institute scientists. Protein from this gene determines whether a head or tail will regrow ...
Biotechnology
May 12, 2011
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Stem cells overflow with potential. Their ability to become other cell types is crucial to our bodies, both during development and throughout life. But this potential can be our very downfall if it goes wrong, turning some ...
Molecular & Computational biology
Sep 30, 2022
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86
Tiny microscopic worms, invisible to the naked eye, are helping scientists to better understand an extraordinarily complex biological pathway that connects fat to overall health and aging in humans.
Cell & Microbiology
Nov 13, 2018
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82
The APC protein serves as the colon's guardian, keeping tumors at bay. Now researchers reveal a new function for the protein: helping to renovate the cytoskeleton by triggering actin assembly. The result suggests a second ...
Cell & Microbiology
Jun 21, 2010
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(Phys.org) —Ever since Robert Hooke first described cells in 1665, scientists have been trying to figure out what is going on inside. One of the most exciting modern techniques involves injecting cells with synthetic genetic ...
Biotechnology
Sep 17, 2014
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In 2012, John B. Gurdon and Shinya Yamakana were awarded the Nobel Prize in medicine for discovering that adult cells can be reprogrammed into pluripotent ones (iPS); the cells obtained are capable of behaving in a similar ...
Cell & Microbiology
May 6, 2014
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Wnt signaling is a well-known mode of cell-to-cell communication in multicellular biological organisms. It involves the secretion of small Wnt glycoproteins, by signaling cells, that bind to receptor proteins in the membrane ...
Molecular & Computational biology
Aug 3, 2023
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66
How cells in developing embryos communicate depends a great deal on context, according to scientists at Rice University.
Cell & Microbiology
Mar 1, 2019
1
47
Cells in humans and other vertebrates, as well as invertebrates, have signaling pathways that play essential roles in embryo development, cell proliferation and tissue structuring. Dysregulation in one of these signaling ...
Cell & Microbiology
Mar 18, 2019
0
106
WNT signaling pathways play important roles in cell growth, development and cancer. The classical or "canonical" WNT pathway and its atypical, "non-canonical" counterpart share a protein called DVL2 that "transduces" or converts ...
Cell & Microbiology
Sep 2, 2019
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