In a landmark technical achievement, investigators in the Vanderbilt Center for Structural Biology have used nuclear magnetic resonance (NMR) methods to determine the structure of the largest membrane-spanning protein to ...
Cell & Microbiology
Jun 25, 2009
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While the presence of harmful critters in your home may be addressed by a call to the exterminator, harmful parasites in the body can be much harder to expel. A single-celled parasite known as Toxoplasma gondii (hereafter ...
Cell & Microbiology
Jun 6, 2023
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19
A new type of drug could provide a way to treat multidrug-resistant bacteria, according to a study published in Nature Communications. Instead of targeting the bacteria directly, the drug blocks key toxins involved in the ...
Cell & Microbiology
Apr 18, 2023
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DNA sequencing has changed biology like nothing else since the origin of species theory. In particular, the way we investigate microbial life has fundamentally changed. Today, we are able to sequence DNA with unprecedented ...
When bacteria interact with other organisms, a myriad of bacterial natural products are involved. In most cases, it is not possible to trace which bacterial strain produces which natural substance and what properties it has. ...
Evolution
May 2, 2022
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97
Microorganisms produce natural products, for example, as disease-causing virulence factors or as defense substances against predators and competitors. A team led by Dr. Robin Teufel and first author Ying Duan from the Institute ...
Biochemistry
Jul 2, 2021
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10
More than half of the world's population carries the bacterium Helicobacter pylori in their stomach mucosa. It often causes no problems throughout life, but sometimes it can cause inflammation, and in some cases, it can even ...
Cell & Microbiology
Oct 15, 2020
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82
Free-swimming cholera bacteria are much less infectious than bacteria in biofilms, aggregates of bacterial cells embedded in a sticky matrix that form on surfaces. This accounts for the surprising effectiveness of filtering ...
Cell & Microbiology
Apr 20, 2020
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86
Tularemia is a rare but often lethal disease. It is caused by one of the most aggressive pathogens on earth, the bacterium Francisella tularensis. The microbe, transported by a variety of animals and insects, is able to enter ...
Analytical Chemistry
Mar 5, 2020
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34
An international team headed by Óscar Llorca at the Spanish National Cancer Research Centre (CNIO), and the group led by Sebastian Geibel at the University of Würzburg (Germany), report an accurate 3-D model of the mechanism ...
Biochemistry
Oct 9, 2019
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