50 year-old protein volume paradox resolved

Durable proteins make life possible in the crushing depths of the ocean, and may have evolved in life below the surface of ice-bound oceanic exo-planets. These proteins stay folded - allowing them to perform their function—under ...

How planarians can regenerate during periods of starvation

Planarians are able to survive long periods of starvation unscathed by maintaining their stem cell pool and regenerative capacity. The molecular processes behind this are not yet known. Jena researchers from the Leibniz Institute ...

Developing new techniques to build biomaterials

Scientists at the University of Leeds have developed an approach that could help in the design of a new generation of synthetic biomaterials made from proteins.

Manipulating stress response in cells could help slow down aging

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have found that a stress response in cells, when "switched on" at a post-reproductive age, could be the key to slow down aging and promote longevity.

Researchers identify key step in viral replication

Viruses are intracellular parasites that cause disease by infecting the cells in the body and, in a study published today in Nature Microbiology, researchers at Children's Hospital of Pittsburgh of UPMC and the University ...

Now researchers can see how unfolded proteins move in the cell

When a large protein unfolds in transit through a cell, it slows down and can get stuck in traffic. Using a specialized microscope—a sort of cellular traffic camera—University of Illinois chemists now can watch the way ...

Cells put off protein production during times of stress

Living cells are like miniature factories, responsible for the production of more than 25,000 different proteins with very specific 3-D shapes. And just as an overwhelmed assembly line can begin making mistakes, a stressed ...

Molecular chaperones help with folding

Chaperones are molecular helpers that assist other proteins with folding. One such chaperone is the so-called heat shock protein 60 (Hsp60). This protein forms structures in mitochondria that resemble barrels in which folding ...

Researchers discover protein protecting against chlorine

Chlorine is a common disinfectant that is used to kill bacteria, for example in swimming pools and drinking water supplies. Our immune system also produces chlorine, which causes proteins in bacteria to lose their natural ...

Cellular stress causes cancer cell chemoresistance

There is a broad range of mechanisms associated with chemoresistance, many of which to date are only poorly understood. The so-called cellular stress response—a set of genetic programs that enable the cells to survive under ...

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