Researchers identify key step in viral replication

Viruses are intracellular parasites that cause disease by infecting the cells in the body and, in a study published today in Nature Microbiology, researchers at Children's Hospital of Pittsburgh of UPMC and the University ...

50 year-old protein volume paradox resolved

Durable proteins make life possible in the crushing depths of the ocean, and may have evolved in life below the surface of ice-bound oceanic exo-planets. These proteins stay folded - allowing them to perform their function—under ...

Molecular chaperones help with folding

Chaperones are molecular helpers that assist other proteins with folding. One such chaperone is the so-called heat shock protein 60 (Hsp60). This protein forms structures in mitochondria that resemble barrels in which folding ...

Researchers discover protein protecting against chlorine

Chlorine is a common disinfectant that is used to kill bacteria, for example in swimming pools and drinking water supplies. Our immune system also produces chlorine, which causes proteins in bacteria to lose their natural ...

Now researchers can see how unfolded proteins move in the cell

When a large protein unfolds in transit through a cell, it slows down and can get stuck in traffic. Using a specialized microscope—a sort of cellular traffic camera—University of Illinois chemists now can watch the way ...

Cells put off protein production during times of stress

Living cells are like miniature factories, responsible for the production of more than 25,000 different proteins with very specific 3-D shapes. And just as an overwhelmed assembly line can begin making mistakes, a stressed ...

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