Related topics: breast cancer · genes · cancer · cancer cells

Structural insights into processes at DNA damage sites

Ishan Deshpande and his colleagues from the group of Susan Gasser and the Protein Structure Facility at the FMI elucidated the mechanism of how Mec1-Ddc2, a tumor suppressor involved in DNA damage response assembles at sites ...

Utilizing tumor suppressor proteins to shape nanomaterials

A new method combining tumor suppressor protein p53 and biomineralization peptide BMPep successfully created hexagonal silver nanoplates, suggesting an efficient strategy for controlling the nanostructure of inorganic materials.

Uncovering a novel mechanism in cell division

Northwestern Medicine scientists have revealed the role amino-terminal methylation plays in a specific protein in the centromere, a region of the chromosome important in cell division, and how the dysregulation of this protein ...

New insights into ubiquitin signalling

Scientists at the University of Würzburg have generated new insights into the intricate molecular underpinnings of ubiquitin signaling. Their results may provide new avenues for cancer therapy.

Human gene prevents regeneration in zebrafish

Regenerative medicine could one day allow physicians to correct congenital deformities, regrow damaged fingers, or even mend a broken heart. But to do it, they will have to reckon with the body's own anti-cancer security ...

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