Many proteins work like Swiss Army knives, fitting multiple functions into their elaborately folded structures. A bit mysteriously, some proteins manage to multitask even with structures that are unfolded and floppy—"intrinsically ...
Cell & Microbiology
Jun 19, 2013
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(Phys.org)—Researchers at Michigan State University have discovered a protein that does its best work with one foot in the grave.
Biochemistry
Dec 12, 2012
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Researchers have shown for the first time that the protein fortilin promotes growth of cancer cells by binding to and rendering inert protein p53, a known tumor suppressor. This finding by researchers at the University of ...
Biochemistry
Sep 16, 2011
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The protein p53 plays an essential role in the prevention of cancer by initiating the controlled death of a cell with damaged genes which is in danger to transform into a cancerous cell. The heat shock protein Hsp90, in turn, ...
Biotechnology
Sep 7, 2011
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(PhysOrg.com) -- A new biophysical and biochemical study may lead to better understanding of how structural flexibility controls the interaction of a protein that is closely involved with cancer, aging and other chronic diseases ...
Biochemistry
Apr 13, 2011
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In proper society of yesterday, the chaperone insured that couples maintained proper courting rituals. In biology, a group of proteins called chaperonins makes sure that proteins are folded properly to carry out their assigned ...
Cell & Microbiology
Jan 20, 2010
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The DNA contained within each of our cells is exactly the same, yet different types of cells - skin cells, heart cells, brain cells - perform very different functions. The ultimate fate of these cells is encoded not just ...
Cell & Microbiology
Jan 6, 2010
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Thousands of scientists and hundreds of software programmers studying the process by which RNA inside cells normally degrades may soon broaden their focus significantly.
Cell & Microbiology
Jul 30, 2009
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Scientists in Michigan and California are reporting an advance toward development of a new generation of drugs that treat disease by orchestrating how genes in the body produce proteins involved in arthritis, cancer and a ...
Biochemistry
Jun 4, 2009
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Often called the building blocks of life, cells are complex and highly dynamic. The genetic information encoded inside enables them to build biomolecular components like proteins, DNA, and RNA, which assemble into larger, ...
Biochemistry
Jan 28, 2021
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