Related topics: patients

Structural insights into processes at DNA damage sites

Ishan Deshpande and his colleagues from the group of Susan Gasser and the Protein Structure Facility at the FMI elucidated the mechanism of how Mec1-Ddc2, a tumor suppressor involved in DNA damage response assembles at sites ...

Combination therapy shown to be effective against canine melanoma

Melanomas are the most common oral cancers in dogs. They are highly metastatic and conventional chemotherapy does not increase survival time. Canine oral melanomas are similar to human melanomas; thus, research is being conducted ...

Checkpoint blockade by a D-peptide for cancer immunotherapy

Our immune system ought to be able to recognize and kill tumor cells. However, many tumors deceive the immune system. For example, they induce the so-called immune checkpoints of T-cells to shut down immune responses. In ...

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