Most approved gene therapies today, including those involving CRISPR-Cas9, work their magic on cells removed from the body, after which the edited cells are returned to the patient.
Biotechnology
Feb 1, 2024
0
112
One problem in gene therapy is that not all genes transfer equally well into the target cells. UZH researchers have now developed a flexible method to transfer large genes efficiently and without significant side effects. ...
Biotechnology
Oct 24, 2023
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61
Over the past decade, researchers have sought more effective and enduring cancer treatments. Among the wide variety of immunotherapies, Stimulator of Interfron Genes activation (STING agonism) has emerged as a particularly ...
Bio & Medicine
Jul 13, 2023
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55
The Hirohide Saito Laboratory has developed cyclic RNA switches that can control gene expression in a cell type-specific manner using miRNAs and RNA-binding proteins and has successfully constructed an artificial gene circuit ...
Cell & Microbiology
Feb 16, 2023
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2
Biofidelity, a genomic technology company, has developed a low-cost, simple and rapid assay for single-molecule detection of multiple gene fusions from RNA. A new scientific paper describes the assay and how detecting these ...
Biotechnology
Oct 19, 2022
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8
Research led by Hong Kong University of Science and Technology (HKUST) has revealed a novel mechanism that regulates secretion of sonic hedgehog (Shh), a key signaling molecule that plays an important role in cancer progression ...
Cell & Microbiology
May 9, 2022
0
27
An emerging type of material called a metal-organic framework (MOF) could help improve the delivery of genetic material for treating disease.
Biochemistry
Apr 11, 2022
0
105
Researchers at MIT and Harvard University have designed a way to selectively turn on gene therapies in target cells, including human cells. Their technology can detect specific messenger RNA sequences in cells, and that detection ...
Biotechnology
Oct 28, 2021
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388
Proteins are the essence of life: they give structure to cells and organelles, catalyze metabolic reactions, build, break, tug, and pull—they carry out most of the actions that sustain a cell's existence.
Biotechnology
Jun 9, 2021
0
10
Scientists at Johns Hopkins Medicine report they have created a tiny, nanosize container that can slip inside cells and deliver protein-based medicines and gene therapies of any size—even hefty ones attached to the gene-editing ...
Bio & Medicine
Dec 6, 2019
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