Scientists at the University of Dundee have reported a major breakthrough in targeting the causes of many diseases, using a `kiss of death' to destroy proteins which had previously been regarded as 'undruggable'.
Biochemistry
Mar 13, 2017
1
19
Inside a living cell, proteins and other molecules are often tightly packed together. These dense clusters can be difficult to image because the fluorescent labels used to make them visible can't wedge themselves in between ...
Bio & Medicine
Aug 29, 2022
0
138
Imagine playing Go Fish with 3,000 cards. Scientists at Rochester Institute of Technology and Dowling College are engaged in a similar game with higher stakes. Instead of cards, they are matching the protein to the job it ...
Cell & Microbiology
Nov 7, 2011
0
0
Researchers at the University of Illinois at Chicago College of Medicine describe for the first time a key target of DNA damage checkpoint enzymes that must be chemically modified to enable stable maintenance of chromosome ...
Cell & Microbiology
Nov 23, 2011
1
0
The fight against antibiotic-resistant superbugs has taken a step forward thanks to a new discovery by scientists at The University of Nottingham.
Cell & Microbiology
Aug 13, 2013
1
0
To better understand how tissues and organs develop, fail to function, and regenerate over time, researchers would like to visualize their constituent cells' repertoires of molecules within 3-D space. Ambitious efforts like ...
Biotechnology
Aug 19, 2019
0
77
The parasites responsible for malaria seem to march to their own beat.
Cell & Microbiology
Jun 10, 2020
0
138
Rice University researchers are making strides toward a set of rules to custom-design Lego-like viral capsid proteins for gene therapy.
Biotechnology
Aug 12, 2013
0
0
(PhysOrg.com) -- In the binding pockets of enzymes their natural binding partners fit exactly. The principle by which many pharmacological agents work also relies on the fact that these substances fit exactly into the pockets ...
Biochemistry
Oct 29, 2009
0
0
Early detection of prostate cancer, one of the most common types of cancer in men, is often achieved with PSA tests. However, this blood test for prostate-specific antigens gives many false positive results, causing unnecessary ...
Biochemistry
Jul 20, 2022
0
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