Successful drug development has a significant impact on people's quality of life worldwide. Being able to track how molecules get into target cells, and observing what they do when they are inside, is key to identifying the ...
Bio & Medicine
Nov 18, 2020
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39
More than half of the world's population carries the bacterium Helicobacter pylori in their stomach mucosa. It often causes no problems throughout life, but sometimes it can cause inflammation, and in some cases, it can even ...
Cell & Microbiology
Oct 15, 2020
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82
A Princeton team has developed a class of light-switchable, highly adaptable molecular tools with new capabilities to control cellular activities. The antibody-like proteins, called OptoBinders, allow researchers to rapidly ...
Cell & Microbiology
Aug 13, 2020
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312
Despite enormous efforts to advance traditional pharmacology approaches, more than three quarters of all human proteins remain beyond the reach of therapeutic development. Targeted protein degradation (TPD) is a novel approach ...
Biochemistry
Aug 3, 2020
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45
Proteins are composed of amino acids connected by amide bonds. The amide bond exhibits high chemical stability and has a planar structure around the bond. Although the high stability of the amide bond is indispensable for ...
Materials Science
Apr 28, 2020
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16
It is the the dream of every molecular geneticist: an easy-to-use program that compares datasets from different cellular conditions, identifies enhancer regions and then assigns them to their target genes. A research team ...
Biotechnology
Nov 27, 2019
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45
A cube one-40th the size of a human red blood cell can glow when it detects flammable gas. The nanocube, designed by chemists at the University of Tokyo, is part of a research project to develop artificial systems that mimic ...
Analytical Chemistry
Sep 13, 2019
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96
The research group of Nuno Maulide from the Faculty of Chemistry of the University of Vienna has, in cooperation with the Research Center for Molecular Medicine (CeMM) of the Austrian Academy of Sciences, achieved the synthesis ...
Biochemistry
Aug 27, 2019
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99
Hepatocyte Growth Factor (HGF) is a protein that acts as a cell growth factor. By binding to its receptor protein MET on the cell membrane, it exerts its physiological functions such as proliferation and migration of cells, ...
Biochemistry
May 29, 2019
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9
There are few things better than the smell of freshly baked bread from the oven; this is because molecules in the bread disperse in the heat to reach your nose. In a similar way, the ExoMars rover Rosalind Franklin will "bake" ...
Space Exploration
May 29, 2019
0
21
