With their potential to treat a wide range of diseases and uncover fundamental processes that lead to those diseases, embryonic stem (ES) cells hold great promise for biomedical science. A number of hurdles, both scientific ...
Cell & Microbiology
Jun 13, 2012
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Many plant and animal pathogens deploy effector proteins as part of their 'molecular arsenal' to facilitate infection and colonisation of their hosts. New research has revealed the structure of a bacterial effector molecule ...
Cell & Microbiology
Jun 11, 2012
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Historically, fly and human Polycomb proteins were considered textbook exemplars of transcriptional repressors, or proteins that silence the process by which DNA gives rise to new proteins. Now, work by a team of researchers ...
Cell & Microbiology
Apr 30, 2012
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(PhysOrg.com) -- A compound found in red wine, grapes and other fruits, and similar in structure to resveratrol, is able to block cellular processes that allow fat cells to develop, opening a door to a potential method to ...
Biochemistry
Apr 4, 2012
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Separating complex mixtures of cells, such as those found in a blood sample, can offer valuable information for diagnosing and treating disease. However, it may be necessary to search through billions of other cells to collect ...
Analytical Chemistry
Feb 22, 2012
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(PhysOrg.com) -- Bacteria are able to build camouflaged homes for themselves inside healthy cells - and cause disease - by manipulating a natural cellular process.
Cell & Microbiology
Dec 20, 2011
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Researchers at the University of Illinois at Chicago College of Medicine describe for the first time a key target of DNA damage checkpoint enzymes that must be chemically modified to enable stable maintenance of chromosome ...
Cell & Microbiology
Nov 23, 2011
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An anti-cancer drug used extensively in chemotherapy binds pervasively to RNA -- up to 20-fold more than it does to DNA, a surprise finding that suggests new targeting approaches might be useful, according to University of ...
Biochemistry
Nov 21, 2011
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Scientists seeking to improve cancer treatments have created a tiny drug transporter that maximizes its ability to silence damaging genes by finding the equivalent of an expressway into a target cell.
Bio & Medicine
Jul 26, 2011
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(Medical Xpress) -- McMaster researchers have discovered a new drug target that may be effective at preventing the onset of Huntington's disease, working much the same way heart medications slow the progression of heart disease ...
Biochemistry
May 31, 2011
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