Since the completion of the Human Genome Project, which identified nearly 20,000 protein-coding genes, scientists have been trying to decipher the roles of those genes. A new approach developed at MIT, the Broad Institute, ...
Biotechnology
Dec 12, 2013
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The protein p53 plays an essential role in the prevention of cancer by initiating the controlled death of a cell with damaged genes which is in danger to transform into a cancerous cell. The heat shock protein Hsp90, in turn, ...
Biotechnology
Sep 7, 2011
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The gene for the protein p53 is the most frequently mutated in human cancer. It encodes a tumor suppressor, and traditionally researchers have assumed that it acts primarily as a regulator of how genes are made into proteins. ...
Cell & Microbiology
Mar 2, 2011
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Johns Hopkins researchers have figured out the specific job of a protein long implicated in tumors of the nervous system. Reporting on a new study described in the Sept. 12 issue of the journal Cell, they detail what they ...
Cell & Microbiology
Sep 11, 2013
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Researchers at the Cell Cycle Research Group of the Bellvitge Institute of Biomedical Research (IDIBELL) led by Ethel Queralt have reported in the journal PLoS Genetics an article which delve into the regulator mechanisms ...
Biotechnology
Dec 11, 2013
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A protein that is crucial for regulating the self-renewal of normal prostate stem cells, needed to repair injured cells or restore normal cells killed by hormone withdrawal therapy for cancer, also aids the transformation ...
Cell & Microbiology
Dec 2, 2010
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The more than 200 different types of human cells have the same DNA but express different ensembles of genes. Each cell type was derived from embryonic stem cells, which are called pluripotent stem cells because they can differentiate ...
Cell & Microbiology
Nov 15, 2017
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A new study sheds light on a little understood biological process called quiescence, which enables blood-forming stem cells to exist in a dormant or inactive state in which they are not growing or dividing. According to the ...
Jan 9, 2009
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A landmark study by Florida State University biologists, in collaboration with scientists in Britain, is the first to identify a life-or-death "cell competition" process in mammalian tissue that suppresses cancer by causing ...
Biotechnology
Jul 13, 2010
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University of Michigan researchers have discovered that a protein known to regulate cellular metabolism is also necessary for normal cell division in blood-forming stem cells. Loss of the protein results in an abnormal number ...
Cell & Microbiology
Dec 1, 2010
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