Investigators explore cellular response to stress

Northwestern Medicine investigators have discovered novel mechanisms that regulate a cell's response to molecular stressors, according to a study published in the Proceedings of the National Academy of Sciences.

Diphthamide is an Achilles heel shared by both plants and animals

The biomolecule diphthamide is essential for the proper formation of proteins in cells. When humans are infected with diphtheria, diphthamide is altered by the diphtheria toxin so that life-threatening complications can arise ...

Supercomputing helps reveal weaknesses in HIV-1 virus

Much remains to be discovered on how the HIV-1 virus infects our cells. Scientists know that it slips past the defenses of our immune system, entering white blood cells to deliver its genetic payload and hijack the cell's ...

Study provides clues on why some bad infections persist

A new study led by researchers at University of Utah Health details a novel mechanism that infectious bacteria use to quickly adjust to environmental stress. The discovery could help explain why certain types of common infections—such ...

Boosted mitochondrial capacity safeguards cells under stress

According to a team of plant researchers, mitochondria provide unexpected help for cells in a crisis by respiring away harmful substances. The current study produced by the Institute of Biology and Biotechnology of Plants ...

Scientists discover how mitochondria import antioxidants

Many of the processes that keep us alive also put us at risk. The energy-producing chemical reactions in our cells, for example, also produce free radicals—unstable molecules that steal electrons from other molecules. When ...

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