Biosynthesis pathway of a new DNA nucleobase elucidated

DNA is composed of nucleobases represented by the letters A, T, G and C. They form the basis of the genetic code and are present in all living beings. But in a bacteriophage, another base, represented by the letter Z, exists. ...

Astronauts demonstrate CRISPR/Cas9 genome editing in space

Researchers have developed and successfully demonstrated a novel method for studying how cells repair damaged DNA in space. Sarah Stahl-Rommel of Genes in Space and colleagues present the new technique in the open-access ...

Putting functional proteins in their place

Scientists have organized proteins—nature's most versatile building blocks—in desired 2D and 3D ordered arrays while maintaining their structural stability and biological activity. They built these designer functional ...

Research advances emerging DNA sequencing technology

Nanopore technology shows promise for making it possible to develop small, portable, inexpensive devices that can sequence DNA in real time. One of the challenges, however, has been to make the technology more accurate.

A protein with a dual role: Both repair and mutation

Using a specialized protein, all bacteria are capable of rapidly and effectively repairing damage to their DNA from UV. However, this mutation frequency decline (Mfd) protein plays another role and causes mutations. A team1 ...

Scientists find a way to accelerate DNA surface hybridization

Scientists globally aim to control chemical reactions—an ambitious goal that requires identifying the steps taken by initial reactants to arrive at the final products as the reaction takes place. While this dream remains ...

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