New method expands the world of small RNAs

A team led by a biomedical scientist at the University of California, Riverside, has developed a new RNA-sequencing method— "Panoramic RNA Display by Overcoming RNA Modification Aborted Sequencing," or PANDORA-seq—that ...

The consequences of mating at the molecular level

While it is known that stem cells have the ability to develop into all tissues in a precisely regulated process, the way environmental cues affect stem cell behavior has remained poorly understood. In a new study, researchers ...

Overcoming genomic imprinting barrier improves mammal cloning

Somatic cell nuclear transfer (SCNT, also known as cloning) technology holds great potential in animal production and regenerative medicine. However, the extremely low efficiency and frequently observed abnormalities in cloned ...

Silencing retroviruses to awaken cell potential

Embryonic stem cells have the potential to differentiate into any type of cell in the human body. Once differentiated though, the newly minted somatic cells live out the rest of their days as that specific cell type and never ...

What's in an egg? Oocyte factors that can reprogram adult cells

The promise of generating truly pluripotent stem cells from terminally differentiated adult cell types continues to captivate scientists who envision great potential for therapeutic interventions. The two primary methods ...

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