Mitochondrial unfolded protein response signals imminent danger

Misfolded proteins must be promptly eliminated as they can form toxic aggregates in cells. LMU biologists have studied how this process is triggered in mitochondria and identified a general alarm signal that activates it.

A protein that pulls the brake on nerve growth

During embryonic development, nerve cells form long, thin extensions that wire up the complex network of the brain. Scientists from the German Center for Neurodegenerative Diseases (DZNE) in Bonn have now identified a protein ...

Controlling movements with light

German researchers at the Ruhr-Universitaet have succeeded in controlling the activity of certain nerve cells using light, thus influencing the movements of mice. By changing special receptors in nerve cells of the cerebellum ...

Scientists discover a key signal in intercellular communication

A team of scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), led by Prof. Francisco Sánchez-Madrid, has characterized a cell signal that impedes intercellular communication and could ...

Chemist devises new method to quantify protein changes

A scientist from the Florida campus of The Scripps Research Institute has devised a new method of analyzing and quantifying changes in proteins that result from a common chemical process. The new findings could provide new ...

A multidimensional view of SARS-CoV-2

What exactly happens when the corona virus SARS-CoV-2 infects a cell? In an article published in Nature, a team from the Technical University of Munich (TUM) and the Max Planck Institute of Biochemistry paints a comprehensive ...

Salk scientists add new bond to protein engineering toolbox

Proteins are the workhorses of cells, adopting conformations that allow them to set off chemical reactions, send signals and transport materials. But when a scientist is designing a new drug, trying to visualize the processes ...

Signal transmission in the immune and nervous system through NEMO

A cascade of various events is required for the transmission of signals within cells. These include several modifications of proteins to switch their function on or off. In order to ensure rapid signal transmission, signaling ...

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