It is rare that an unpublished piece of research or theory remains significant after half a century. It is also a wonderful example of the boundless curiosity of the late Francis Crick. A previously unpublished work by Francis ...
Cell & Microbiology
Apr 18, 2013
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Majority of human Src homology 2 domains not only bind to proteins, but also interact with membrane lipids with high affinity and specificity. The SH2 domain-containing proteins play important roles in various physiological ...
Cell & Microbiology
Mar 28, 2016
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Most animals have a dorso-ventral (back-to-belly) body axis, which determines for instance the localized position of the central nervous system, dorsal in humans, ventral in insects. Surprisingly, despite enormous morphological ...
Cell & Microbiology
Mar 18, 2015
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All organisms react to different external and internal stimuli: if, for example, the hyphae fungus Sordaria macrospora is supplied with food, it produces fruiting bodies as part of its oestrous cycle. To initiate this reaction, ...
Biotechnology
Sep 4, 2014
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In a structural analysis that could help inform efforts to develop new drugs for treating a myriad of diseases, RIKEN biologists have shed light on how the interaction between key signaling proteins and their regulatory partners ...
Cell & Microbiology
Mar 15, 2022
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According to a theoretical model developed by LMU physicists, in cell protrusions, cargo-transporting motor proteins often get in each other's way. The upshot is that freely diffusing proteins reach the leading edge faster.
General Physics
Mar 27, 2017
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Cellular signaling pathways involved in everything from the proliferation of fatty tissue to the death of neurons in the brain are tightly regulated by "cascades" of sequentially activated enzymes, MAP kinases. These enzymes ...
Cell & Microbiology
Jan 21, 2019
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