Researchers reveal a new way in which cells restrain beta-catenin and potentially suppress tumor metastasis: the protein can be ejected from cells in small vesicles called exosomes. The study appears online on September 13 ...
Cell & Microbiology
Sep 13, 2010
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Using state-of-the-art electron microscopy techniques, a team led by researchers from Caltech has for the first time visualized and described the precise arrangement of chemoreceptors—the receptors that sense and respond ...
Cell & Microbiology
Sep 24, 2009
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Signal transduction and perception regulates biological activities to adapt to changing environments. The Pert-Arnt-Sim domains are commonly available sensors found across diverse receptors in bacteria, eukaryotes, and archaea. ...
A team of researchers from Spain, Germany and France has identified the gene switch ENO (excessive number of floral organs) as a tomato fruit regulator. In their paper published in Proceedings of the National Academy of Sciences, ...
By combining the tools of medicinal chemistry and zebrafish biology, a team of Vanderbilt investigators has identified compounds that may offer therapeutic leads for bone-related diseases and cancer.
Biochemistry
Jan 21, 2010
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As animals explore their environment, they learn to master it. By discovering what sounds tend to precede predatorial attack, for example, or what smells predict dinner, they develop a kind of biological clairvoyance—a ...
Cell & Microbiology
Jun 26, 2019
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Supercomputer simulations by RIKEN researchers have revealed how drug binding to a protein target changes as the surrounding environment becomes more cluttered with other proteins. These simulations could help improve drug ...
Biotechnology
Oct 21, 2021
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Biology is on the verge of getting its versions of the lever, wheel and axle, pulley and other basic machines that enable engineers to build almost any mechanical device, a new analysis has concluded. The viewpoint article ...
Biotechnology
Jun 5, 2013
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(PhysOrg.com) -- Using a rare metal that's not utilized by nature, Rice University chemists have created a synthetic enzyme that could help unlock the identities of thousands of difficult-to-study proteins, including many ...
Biochemistry
Apr 28, 2010
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Fruit flies provide an effective platform for screening new obesity genes, and fat flies implicate a neuronal signaling pathway in weight gain, according to a new study publishing November 4th in the open-access journal PLOS ...
Molecular & Computational biology
Nov 4, 2021
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